Effects of phenolic compounds on alterations caused by disruption of the circadian rhythm

Poster European Corner

Nom i cognoms / Name and surname

Fabiola García Reyes

Afiliació / Affiliation

Universitat Rovira i Virgili

Programa de finançament europeu en que s’enmarca aquest projecte? / European funding programme in which this project is being carried out?

Marie Skłodowska-Curie Schemes

 Títol del projecte / Project title

Effects of phenolic compounds on alterations caused by disruption of the circadian rhythm

 Número del projecte / Project number

Marie Skłodowska-Curie grant agreement No. 945413/ PID2021-128813OB-I00

Breu explicació del projecte / Brief explanation of your project

Biological processes are internally regulated by the master and peripheral clocks following cycles of roughly 24h governed by light-dark cues. Disruption of the circadian rhythm caused by shiftwork, jet lag, or irregular sleep patterns has been associated with various health problems, such as metabolic disorders and cardiovascular disease. Interestingly, GSPE, a dietary phenolic compound found in grape seeds has been shown to have potential health benefits, including antioxidant and anti-inflammatory effects. Moreover, previous studies in our research group suggest that GSPE can modulate physiology and metabolism via the peripheral and central molecular clocks possibly protecting against circadian rhythm disruption. In this study, we aim to investigate the potential effects of GSPE on the metabolic alterations caused by the disruption of the circadian rhythm in a rat model. This study highlights the importance of understanding the potential effects of bioactive compounds in the context of circadian rhythm disruption and suggests that further research is needed to identify potential interventions for the management of circadian rhythm-related health problems.

 Enllaç a la pàgina web del projecte / Link to your project website


Repte en que s’emmarca aquest projecte / Challenge within the framework of this project

Does not apply



Amb el suport de:

Amb el finançament de:

Aquest projecte està cofinançat pel programa de recerca i innovació Horizon Europe de la Unió Europea sota el projecte NitRecerCat (101061189).

This project is co-funded by the European Union’s research and innovation programme Horizon Europe, under the project NitRecercat (101061189).