Nom i cognoms / Name and surname
Fabiola García Reyes
Afiliació / Affiliation
Universitat Rovira i Virgili
Programa de finançament europeu en que s’enmarca aquest projecte? / European funding programme in which this project is being carried out?
Marie Skłodowska-Curie Schemes
Títol del projecte / Project title
Effects of phenolic compounds on alterations caused by disruption of the circadian rhythm
Número del projecte / Project number
Marie Skłodowska-Curie grant agreement No. 945413/ PID2021-128813OB-I00
Breu explicació del projecte / Brief explanation of your project
Biological processes are internally regulated by the master and peripheral clocks following cycles of roughly 24h governed by light-dark cues. Disruption of the circadian rhythm caused by shiftwork, jet lag, or irregular sleep patterns has been associated with various health problems, such as metabolic disorders and cardiovascular disease. Interestingly, GSPE, a dietary phenolic compound found in grape seeds has been shown to have potential health benefits, including antioxidant and anti-inflammatory effects. Moreover, previous studies in our research group suggest that GSPE can modulate physiology and metabolism via the peripheral and central molecular clocks possibly protecting against circadian rhythm disruption. In this study, we aim to investigate the potential effects of GSPE on the metabolic alterations caused by the disruption of the circadian rhythm in a rat model. This study highlights the importance of understanding the potential effects of bioactive compounds in the context of circadian rhythm disruption and suggests that further research is needed to identify potential interventions for the management of circadian rhythm-related health problems.
Enllaç a la pàgina web del projecte / Link to your project website
https://www.nutrigenomica.recerca.urv.cat/ca/recerca/projectes/
Repte en que s’emmarca aquest projecte / Challenge within the framework of this project
Does not apply
