EChiLiBRiST

Ciutat:
Poster European Corner

Nom i cognoms / Name and surname

Carole Amroune

Afiliació / Affiliation

ISGlobal

Programa de finançament europeu en que s’enmarca aquest projecte? / European funding programme in which this project is being carried out?

EU support (FP7, H2020, etc.) other than MSCA

Títol del projecte / Project title

EChiLiBRiST – Development and validation of a quantitative point-of-care test for the measurement of severity biomarkers to improve risk stratification of fever syndromes and enhance child survival

Número del projecte / Project number

101057114

Breu explicació del projecte / Brief explanation of your project

The EU-funded Project EChiLiBRiST will develop and trial a rapid test for the early recognition and management of febrile patients at risk ofsevere disease.
During the first 2 years, we will develop and validate a laboratory prototype, as well as develop a functional prototype to produce mini-series to test in the field. During the next 3 years, we will perform clinical trials in 3 different African countries to determine its performance in febrile children, in terms of appropriately supporting the decision of hospital admission compared to the standard of care triaging approaches. In addition, we will determine the effectiveness of L-citrulline supplementation (targeting endothelial activation) in improving long-term outcomes among children risk-stratified by our test. Finally, these trials will be accompanied by health impact and economic modelling of nation-wide introduction of the test, as well as feasibility and acceptance of the rapid triage strategy by healthcare providers and community.

Enllaç a la pàgina web del projecte / Link to your project website

www.echilibrist.org

Repte en que s’emmarca aquest projecte / Challenge within the framework of this project

Does not apply

Coordinen:

Amb el suport de:

Amb el finançament de:

Aquest projecte està cofinançat pel programa de recerca i innovació Horizon Europe de la Unió Europea sota el projecte NitRecerCat2425 (101162003).

This project is co-funded by the European Union’s research and innovation programme Horizon Europe, under the project NitRecercat2425 (101162003).