Nom i cognoms / Name and surname
Nicholus Bhattacharjee
Afiliació / Affiliation
Zymvol Biomodeling SL
Programa de finançament europeu en que s’enmarca aquest projecte? / European funding programme in which this project is being carried out?
Marie Skłodowska-Curie Schemes
Títol del projecte / Project title
Software development for biocatalytic process optimization (Tecniospring INDUSTRY)
Número del projecte / Project number
COFUND-MSCA 801342
Breu explicació del projecte / Brief explanation of your project
The project which is also know as ENZIMMO-P (ENZyme IMMobilization Platform) has two main goals: (1) To develop a software able to speed up the optimization stage of His-tag based affinity immobilization exercises (ZYMVOLVER-iMMO), and (2) Apply it for the efficient immobilization of a proprietary peroxygenase (gzPO). The process of enzyme immobilization on solid surfaces provides several industrial advantages which include easier reusability, enzyme recovery, generally improved enzyme stability under storage and operating conditions, enhanced activity, optimized selectivity or specificity, etc. The currently used immobilization protocols are empiric-based in nature and need extensive screening and condition optimization. In this current project we are designing an in silico protocol to allow a highly efficient, cost-effective enzyme immobilization. Furthermore, Zymvol in collaboration with Gecco Biotech has recently developed a set of proprietary peroxygenases (gzPO) which show enhanced stability and whose immobilization would boost their industrial application. The immobilization protocol developed in this project will be applied to immobilize the gzPO efficiently.
Enllaç a la pàgina web del projecte / Link to your project website
https://zymvol.com/enzymes-research/#projects
Repte en que s’emmarca aquest projecte / Challenge within the framework of this project
Does not apply
